Israeli forces killed five gunmen in a mosque in the West Bank's Tulkarem, according to a joint statement released by the Israeli military and Shin Bet security service and border police.
Among those killed was Muhammad Jaber, known as Abu Shujaa, who Israeli intelligence agencies accuse of planning a shooting in June that killed an Israeli man.
The Israeli military said another militant was arrested in the operation in Tulkarem, and that a member of Israel's paramilitary Border Police was lightly wounded.
Israel launched a large-scale operation in the West Bank overnight into Wednesday.
Islamic Jihad group confirms regional commander's death
The Palestinian militant group Islamic Jihad announced the death of its commander in the Nur Shams refugee camp in Tulkarem, where the Israeli military said it had "eliminated" five militants on Thursday.
They included Muhammad Jabber, also known as Abu Shujaa.
"Abu Shujaa, commander of the Tulkarem Brigade of the Al-Quds Brigades," the armed wing of Islamic Jihad, "died along with several brothers of his brigade after a heroic battle against the soldiers of the [Israeli] occupation", the group said in a statement.
Islamic Jihad has been designated a terrorist organization in multiple jurisdictions, including the United States, the European Union and Israel.